THE JOHN CHARNLEY AWARD: A Study
of Implant Failure in Metal-on-Metal Surface Arthroplasties.
Clin Orthop Relat Res. 2006 Aug
10
Campbell P,
Beaule PE,
Ebramzadeh E,
Leduff M,
De Smet K,
Lu Z,
Amstutz HC.
The reintroduction of surface arthroplasty
of the hip with metal-on-metal bearings has the potential to eliminate
or substantially reduce long-term wear-induced osteolysis as the major
cause of failure. To determine important modes of failure, implant retrieval
analysis was done on 98 failed surface arthroplasty components from different
manufacturers. Analysis involved sectioning the components, measuring
cement mantle thickness and the depth of penetration, histopathology,
and measurement of the bearing wear. A finite element model was constructed
to examine cement thermal necrosis. Femoral neck fracture and femoral
loosening were the main causes of failure. The finite element model showed
thermal necrosis could occur when cysts were filled with cement. Histologic
observations verified necrosis of interfacial bone, although adaptive
remodeling was commonly seen. The amount of cement varied considerably
with implant type, and failure mode and was greater in loosened components.
Although implant failure is multifactorial, these observations should
be a cause for concern in current cementing techniques in which controlling
mantle thickness and extent of penetration may be difficult. Optimizing
cement technique to avoid leaving the component proud, and to avoid extensive
cementation of the femoral head, may be important in reducing some modes
of failure.